Wrenches and ratchets accomplish the same job — tightening and loosening fasteners — but there are variances and situations that need one over the other. A box-end wrench, for example, is a fantastic alternative for releasing stuck fasteners since it allows you to apply more force without risking ratchet mechanism damage. A wrench with an open-end fit around a fastener rather than over it, allowing it to be used in places where a socket would not fit. Always be sure the tool you're using is appropriate for the job at hand.
Some of the factors to consider in designing or selecting a safe series of wrenches and fasteners include maximum tightening torque, maximum removal torque, minimum torsional strength, and torques from wrench specifications.